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Iridium‐Catalyzed H/D Exchange
Author(s) -
Krüger Jens,
Manmontri Boripont,
Fels Gregor
Publication year - 2005
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200400669
Subject(s) - chemistry , iridium , catalysis , scope (computer science) , labelling , medicinal chemistry , organic chemistry , biochemistry , computer science , programming language
The scope and limitation of an iridium‐catalysed H/D exchange reaction has been investigated. Our results suggest a general mechanism for specific labelling at aromatic and non‐aromatic double bonds by D 2 O if an electron‐donating group is in a 1,4‐relation with the carbon where the H/D exchange takes place. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)