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A Highly Effective (Triphenyl phosphite)palladium Catalyst for a Cross−Coupling Reaction of Allylic Alcohols with Organoboronic Acids
Author(s) -
Kayaki Yoshihito,
Koda Takashi,
Ikariya Takao
Publication year - 2004
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200400621
Subject(s) - chemistry , allylic rearrangement , palladium , catalysis , reagent , aryl , triphenyl phosphite , organic chemistry , organoboron compounds , toluene , coupling reaction , medicinal chemistry , alkyl
The cross coupling reaction of aryl and vinyl boronic acids and allylic alcohols proceeded smoothly in toluene or dioxane in the presence of a (triphenyl phosphite)palladium catalyst to give the corresponding allylbenzene derivatives and 1,4‐dienes. Neither cocatalysts for promoting C−O bond cleavage of allylic alcohols nor bases for activation of organoboron reagents are required for promoting the coupling process. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)