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Aquapalladium Complex: A Stable and Convenient Catalyst for the Intermolecular Hydroamination of Alkynes
Author(s) -
Shimada Tomohiro,
Bajracharya Gan B.,
Yamamoto Yoshinori
Publication year - 2005
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200400568
Subject(s) - hydroamination , chemistry , intermolecular force , catalysis , alkyne , medicinal chemistry , organic chemistry , combinatorial chemistry , molecule
The intermolecular hydroamination of alkynes proceeds very smoothly in the presence of a catalytic amount of the aquapalladium complex [Pd(dppe)(H 2 O) 2 ](TfO) 2 . This reaction most probably proceeds through the formation of an equilibrium between the hydroxopalladium and the amidopalladium complexes, and subsequent aminopalladation of alkynes. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)