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Nucleophile‐Selective Selenocyclizations
Author(s) -
Khokhar Shaista S.,
Wirth Thomas
Publication year - 2004
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200400526
Subject(s) - electrophile , chemistry , nucleophile , stereoselectivity , counterion , selenium , organic chemistry , umpolung , combinatorial chemistry , catalysis , ion
Electrophilic cyclizations are one of the major strategies for cyclofunctionalizations of alkenes. Selective selenocyclizations can be performed by adjusting various factors in such reactions. The nature of the electrophile, the counterion, solvents, and external additives coordinating to the electrophilic species are used to control the course of such cyclizations with high degrees of efficiency. Our investigations have been extended towards stereoselective reactions using chiral selenium electrophiles. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)