Premium
Synthesis of Methylene‐ and Methine‐Bridged Oligopyridines
Author(s) -
Dyker Gerald,
Muth Oliver
Publication year - 2004
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200400435
Subject(s) - chemistry , methylene , nucleophilic substitution , nucleophilic aromatic substitution , medicinal chemistry , stereochemistry
A variety of methylene‐ and methine‐bridged oligopyridines are conveniently accessible through stepwise nucleophilic aromatic substitution with fluoro‐substituted pyridines. The yields achieved are regularly above 90%. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)