Intramolecular Ritter Reactions of 2‐(2‐Cyanoethyl)tetrahydrocyclopenta[ b ]indole and ‐carbazole Derivatives | Zendy

Maertens Faye | Zendy; Van den Bogaert An  | Zendy; Compernolle Frans | Zendy; Hoornaert Georges J. | Zendy

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Intramolecular Ritter Reactions of 2‐(2‐Cyanoethyl)tetrahydrocyclopenta[ b ]indole and ‐carbazole Derivatives

Author(s) -

Maertens Faye,

Van den Bogaert An ,

Compernolle Frans,

Hoornaert Georges J.

Publication year - 2004

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.200400409

Subject(s) - chemistry , indole test , ritter reaction , carbazole , intramolecular force , stereochemistry , intramolecular reaction , medicinal chemistry , organic chemistry , catalysis

Intramolecular Ritter reactions of 2‐(2‐cyanoethyl)tetrahydrocyclopenta[ b ]indole and ‐carbazole derivatives, prepared by a sequence of two different α‐substitutions and Grignard reactions of the indole‐based ketones 4‐methyl‐1,4‐dihydrocyclopenta[ b ]indol‐3(2 H )‐one and 9‐methyl‐2,3,4,9‐tetrahydro‐1 H ‐carbazol‐1‐one, were used as key steps in the construction of various tetracyclic lactam compounds. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)

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