TAME‐Hex A − A Novel Bifunctional Chelating Agent for Radioimmunoimaging | Zendy

Arslantas Enver | Zendy; SmithJones Peter M. | Zendy; Ritter Gerd | Zendy; Schmidt Richard R. | Zendy

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TAME‐Hex A − A Novel Bifunctional Chelating Agent for Radioimmunoimaging

Author(s) -

Arslantas Enver,

SmithJones Peter M.,

Ritter Gerd,

Schmidt Richard R.

Publication year - 2004

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.200400224

Subject(s) - bifunctional , chemistry , chelation , combinatorial chemistry , stereochemistry , organic chemistry , catalysis

Two novel (bifunctional) chelating agents, TAME‐Hex A and B, which are polyaminopolycarboxylic acids based on the tripodal TAME [tris(aminomethyl)ethane] structure, have been designed and synthesized. The chelators show very good stability with gallium( III ) ions and thus are highly effective candidates for use in radioimmunoimaging (RII), especially in positron emission tomography (PET). (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)

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