Premium
Synthesis and Conformational Analysis of Macrocycles Related to 10‐Oxa‐epothilone
Author(s) -
Quintard Delphine,
Bertrand Philippe,
Bachmann Christian,
Gesson JeanPierre
Publication year - 2004
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200400212
Subject(s) - chemistry , ring closing metathesis , epothilone , stereochemistry , aldehyde , metathesis , salt metathesis reaction , ring (chemistry) , organic chemistry , catalysis , polymerization , polymer
A short and convergent synthesis of macrocyclic lactones related to 10‐oxa‐epothilone is based on aldolisation of a 3‐(2′‐methylallyloxy) aldehyde derived from methyl (2 S )‐3‐hydroxy‐2‐methylpropionate followed by ring‐closing metathesis. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom