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Cover Picture: The Effect of High Pressure on the Heck Reaction − A Contribution to a Deeper Understanding of the Mechanism (Eur. J. Org. Chem. 13/2003)
Author(s) -
Buback Michael,
Perković Thomas,
Redlich Stefan,
Meijere Armin de
Publication year - 2003
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200390228
Subject(s) - chemistry , heck reaction , palladium , reaction mechanism , coupling reaction , catalysis , atmospheric pressure , computational chemistry , high pressure , photochemistry , organic chemistry , thermodynamics , meteorology , physics
The cover picture shows the influence of high pressure on the Heck cross‐coupling reaction. As reflected by its generally accepted mechanism, this palladium‐catalyzed reaction proceeds in a number of distinctly different steps, some of which ought to be retarded by high pressure. Yet, the overall effect leads to a significant acceleration, and the reaction has a negative volume of activation. The kinetic parameters were determined by monitoring the reaction in a massive metal cylinder − as seen in the background − by on‐line FT‐IR spectroscopy. Details are discussed in the article by A. de Meijere et al. on p. 2375 ff.