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A Stereoselective Synthesis of Five‐ and Six‐Membered Cyclic β‐Amino Acids
Author(s) -
Perlmutter Patrick,
Rose Mark,
Vounatsos Filisaty
Publication year - 2003
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200390118
Subject(s) - chemistry , stereoselectivity , imine , ring closing metathesis , metathesis , salt metathesis reaction , stereochemistry , thioester , total synthesis , amino acid , enantioselective synthesis , organic chemistry , catalysis , polymerization , biochemistry , polymer , enzyme
The cyclic β‐amino acids 1 and 2 have been prepared in a short and stereoselective manner. The synthesis features a diastereoselective thioester enolate/imine condensation reaction and a ring‐closing metathesis as key processes. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)

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