Premium
Vicarious Nucleophilic Substitution of (Chloroalkyl)heterocycles with Nitroarenes
Author(s) -
Florio Saverio,
Lorusso Patrizia,
Luisi Renzo,
Granito Catia,
Ronzini Ludovico,
Troisi Luigino
Publication year - 2004
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200300806
Subject(s) - chemistry , benzothiazole , thiazole , carbanion , nucleophilic substitution , nucleophile , medicinal chemistry , substitution reaction , potassium , substitution (logic) , organic chemistry , stereochemistry , catalysis , programming language , computer science
The vicarious nucleophilic substitution of potassium carbanions of the (chloromethyl)pyridines 1a and 1b , (chloromethyl)benzothiazole 1c , (chloromethyl)thiazole 1d , (chloroethyl)thiazole 1e and (chloroethyl)benzothiazole 1f with nitroarenes, leading to nitrobenzyl heterocycles 2 and 4 − 14 has been studied. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)