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Synthesis of (±)‐17‐Methylcamptothecins
Author(s) -
Thomas Olivier P.,
Dumas Cécile,
Zaparucha Anne,
Husson HenriPhilippe
Publication year - 2004
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200300565
Subject(s) - chemistry , surface modification , ring (chemistry) , combinatorial chemistry , stereochemistry , organic chemistry
(±)‐17‐Methylcamptothecins ( 29 ) were synthesized from the heteroyohimbane ajmalicine ( 5 ) through sequential oxidation steps and E‐ring functionalization. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)