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Lithium Perchlorate‐Catalyzed Three‐Component Coupling: A Facile and General Method for the Synthesis of α‐Aminophosphonates under Solvent‐Free Conditions
Author(s) -
Azizi Najmedin,
Saidi Mohammad R.
Publication year - 2003
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200300479
Subject(s) - chemistry , lithium perchlorate , solvent , catalysis , lithium (medication) , perchlorate , coupling (piping) , organic chemistry , combinatorial chemistry , ammonium perchlorate , component (thermodynamics) , inorganic chemistry , ion , metallurgy , electrochemistry , physics , thermodynamics , medicine , materials science , electrode , endocrinology
A simple, efficient, and general method has been developed for the synthesis of α‐aminophosphonates in the presence of solid lithium perchlorate under solvent‐free conditions. Thus secondary and tertiary α‐aminophosphonates were synthesized relatively quickly in good yields at room temperature. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)

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