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Synthetic Study on Campylobacter jejuni Lipopolysaccharides: An Improved Synthesis of a Branched, Heptose‐Containing Trisaccharide Core Structure and Its Conversion into Ganglioside GD3 Related Hexasaccharide
Author(s) -
Hori Koji,
Sawada Naoki,
Ando Hiromune,
Ishida Hideharu,
Kiso Makoto
Publication year - 2003
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200300309
Subject(s) - trisaccharide , chemistry , campylobacter jejuni , heptose , ganglioside , stereochemistry , epitope , oligosaccharide , biochemistry , bacteria , antigen , genetics , mutant , gene , biology
The first synthesis of the oligosaccharide skeleton of the Campylobacter jejuni lipooligosaccharide composed of a branched, heptose‐containing trisaccharide core structure and, including a substantially improved preparation of the core structure, the ganglioside GD3 related trisaccharide epitope is reported. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)