Ten‐Membered Substituted Cyclic 2‐Oxecanone (Decalactone) Derivatives from Latrunculia corticata , a Red Sea Sponge

Two novel glycosides, latrunculinosides A and B, containing substituted 2‐oxecanones (decalactones) were isolated from Latrunculia corticata collected in the Gulf of Aqaba, Israel. They were characterized by spectroscopic methods, predominantly 1 H NMR, 13 C NMR, MS, IR and UV, and by chemical degradation. Both glycosides contain unusual saccharides such as β‐ D ‐olivose, β‐ L ‐digitoxose, α‐ L ‐amicetose, and β‐ D ‐oliose. The compounds gave positive results in antifeeding activity assays. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)