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An Efficient Total Synthesis of Pedunculagin by Using a Twofold Intramolecular Double Esterification Strategy
Author(s) -
Khanbabaee Karamali,
Großer Mathias
Publication year - 2003
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200300006
Subject(s) - chemistry , intramolecular force , total synthesis , sugar , stereochemistry , organic chemistry , combinatorial chemistry
The total synthesis of naturally occurring pedunculagin ( 1 ) was achieved by the twofold intramolecular double esterification of enantiomerically pure ( S )‐hexabenzyloxydiphenic acid ( 4 ) with the D ‐glucose‐derived sugar 2 as the key step. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)