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Lewis Acidic Chloroaluminate Ionic Liquids: Novel Reaction Media for the Synthesis of 4‐Chloropyrans
Author(s) -
Yadav Jhillu S.,
Reddy Basi V. S.,
Reddy Maddi Sridhar,
Niranjan Namelikonda,
Prasad Attaluri R.
Publication year - 2003
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200210638
Subject(s) - ionic liquid , chemistry , catalysis , solvent , lewis acids and bases , organic chemistry , lewis acid catalysis , inorganic chemistry
Abstract 1 ‐ n ‐Butyl‐3‐methylimidazolium chloroaluminate [bmim]Cl·AlCl 3 ( N = 0.56−0.67) ionic liquid has been employed as an alternative reaction medium to conventional acid catalysts for Prins cyclizations, to produce 4‐chlorotetrahydropyran derivatives in excellent yields and in short reaction times. The ionic liquid plays a dual role as both catalyst and solvent, providing a rapid and efficient route to the synthesis of chlorotetrahydropyrans. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)