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Bioorganic Chemistry of Ceramide
Author(s) -
Brodesser Susanne,
Sawatzki Peter,
Kolter Thomas
Publication year - 2003
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200200518
Subject(s) - ceramide , chemistry , bioorganic chemistry , sphingolipid , biochemistry , lipid signaling , membrane , organic chemistry , enzyme , apoptosis
Ceramide is the hydrophobic membrane anchor of glycosphingolipids, a vital component of the human skin, and a novel signaling substance. We give an overview of ceramide analogues that have been prepared to address biochemical questions related to the various functions of this lipid. We also discuss possible therapeutic applications. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)