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Evaluation of a model system for the selective study of the lipid peroxidation process
Author(s) -
Mihaljević Branka,
Tartaro Ivana,
Filipović Vinceković Nada
Publication year - 2012
Publication title -
european journal of lipid science and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.614
H-Index - 94
eISSN - 1438-9312
pISSN - 1438-7697
DOI - 10.1002/ejlt.201200116
Subject(s) - ferrous , chemistry , lipid peroxidation , polyunsaturated fatty acid , pulmonary surfactant , micelle , radical , ferric , linoleic acid , oxidative phosphorylation , fatty acid , chromatography , inorganic chemistry , antioxidant , aqueous solution , organic chemistry , biochemistry
The effect of molecular environment on the peroxidation of linoleic acid (LA), a polyunsaturated fatty acid (PUFA), initiated by ferrous ions was investigated in acidic and neutral pH conditions. Mixed nonionic surfactants TWEEN®‐20/LA micelles were established as a model system to obtain a surfactant‐in‐lipid aqueous system at high acidity level. The peroxidation of LA was induced by ferrous ions and the kinetics of the produced conjugated dienes was followed by UV measurements and the ferric thiocynate method. Ferrous ions were oxidized only by the preformed LA hydroperoxides, which under established conditions produced lipid alkoxyl and peroxyl radicals as the sole initiators of propagation. The results revealed the LA peroxidation process remained mainly unaffected within the 2.5