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A review of lipidomic technologies applicable to sphingolipidomics and their relevant applications
Author(s) -
Han Xianlin,
Jiang Xuntian
Publication year - 2009
Publication title -
european journal of lipid science and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.614
H-Index - 94
eISSN - 1438-9312
pISSN - 1438-7697
DOI - 10.1002/ejlt.200800117
Subject(s) - biochemical engineering , chemistry , computational biology , nanotechnology , engineering , materials science , biology
Sphingolipidomics, a branch of lipidomics, focuses on the large‐scale study of the cellular sphingolipidomes. In the current review, two main approaches for the analysis of cellular sphingolipidomes ( i.e. LC‐MS‐ or LC‐MS/MS‐based approach and shotgun lipidomics‐based approach) are briefly discussed. Their advantages, some considerations of these methods, and recent applications of these approaches are summarized. It is the authors' sincere hope that this review article will add to the readers understanding of the advantages and limitations of each developed method for the analysis of a cellular sphingolipidome.