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The role of retinoids and their receptors in metabolic disorders
Author(s) -
Meissburger Bettina,
Wolfrum Christian
Publication year - 2008
Publication title -
european journal of lipid science and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.614
H-Index - 94
eISSN - 1438-9312
pISSN - 1438-7697
DOI - 10.1002/ejlt.200700291
Subject(s) - retinoid x receptor gamma , retinoic acid , retinoid , retinoid x receptor alpha , retinoic acid inducible orphan g protein coupled receptor , receptor , retinoid x receptor , retinoid x receptor beta , nuclear receptor , retinoic acid receptor alpha , retinoic acid receptor gamma , retinoic acid receptor , retinoic acid receptor beta , biochemistry , biology , chemistry , microbiology and biotechnology , transcription factor , gene
Retinoid derivatives are potent regulators of a wide variety of cellular functions through the modulation of nuclear receptor activity. Three distinct families of retinoid receptors have been identified so far, namely retinoic acid receptors, retinoic acid X receptors, and retinoic acid‐related orphan receptors. This review focuses on retinoid signaling and the regulation of metabolic processes by the family of retinoic acid receptors in relation to the development of metabolic disorders.