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Occurrence of dyslipidemia in spontaneous intracerebral hemorrhage
Author(s) -
Herzig Roman,
Vlachová Ivanka,
Mareš Jan,
Křupka Bohdan,
Gabryš Martin,
Vaverková Helena,
Šaňák Daniel,
Schneiderka Petr,
Buřval Stanislav,
Kaňovský Petr
Publication year - 2006
Publication title -
european journal of lipid science and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.614
H-Index - 94
eISSN - 1438-9312
pISSN - 1438-7697
DOI - 10.1002/ejlt.200500285
Subject(s) - dyslipidemia , medicine , intracerebral hemorrhage , neurology , gastroenterology , statistical significance , neurosurgery , hypocholesterolemia , clinical chemistry , cholesterol , lipidology , surgery , subarachnoid hemorrhage , disease , psychiatry
Background: Dyslipidemia, mainly hypocholesterolemia is considered to be a risk factor (RF) for spontaneous intracerebral hemorrhage (SICH). The aim of our study was to assess its role in our SICH patients. Methods: In a hospital‐based cross‐section study, laboratory assessments of total cholesterol (TC), triglycerides (TG), high‐density cholesterol (HDL‐C) and low‐density cholesterol (LDL‐C) plasma levels were performed in 80 SICH patients without vascular malformation and in a control group (CG) of 80 age‐ and sex‐matched patients with low back pain. All patients were treated at the Departments of Neurology and Neurosurgery, University Hospital, Olomouc, Czech Republic. Two‐sample t ‐test and Mann‐Whitney test were applied when assessing statistical significance. Results: The following mean lipid plasma levels were found in SICH patients versus CG subjects (in mmol/L): TC, 5.89 vs. 5.48 ( p = 0.007); TG, 1.31 vs. 2.10 ( p <0.0001); HDL‐C, 1.58 vs. 1.33 ( p = 0.0001); LDL‐C, 3.70 vs. 3.18 ( p = 0.0004). Conclusions: TC and LDL‐C plasma levels were higher in SICH patients in the Olomouc region of the Czech Republic.