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Nematicidal sphingolipids from the freshwater fungus Paraniesslia sp. YMF1.01400
Author(s) -
JinYan Dong,
Ru Li,
HongPing He,
KeQin Zhang
Publication year - 2005
Publication title -
european journal of lipid science and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.614
H-Index - 94
eISSN - 1438-9312
pISSN - 1438-7697
DOI - 10.1002/ejlt.200500219
Subject(s) - fungus , sphingolipid , chemistry , stereochemistry , mycelium , in vitro , biochemistry , biology , microbiology and biotechnology , botany
A new ( 1 ) and a known ( 2 ) sphingolipid were isolated from mycelial cultures of Paraniesslia sp. YMF1.01400. The structures of these two isolates were elucidated as (2 S ,2' R ,3 R ,3' E ,4 E ,8 E )‐1‐O‐(β‐ D ‐glucopyranosyl)‐3‐hydroxyl‐2‐[N‐2'‐hydroxyl‐3'‐eico‐sadecenoyl]amino‐9‐methyl‐4,8‐octadecadiene ( 1 ) and (2 S ,2' R ,3 R ,3' E ,4 E ,8 E )‐1‐O‐(β‐ D ‐glucopyranosyl)‐3‐hydroxyl‐2‐[N‐2'‐hydroxyl‐3'‐octadecenoyl]amino‐9‐methyl‐4,8‐octadecadiene ( 2 ) by spectroscopic and chemical methods. In in vitro tests, both compounds showed moderate nematicidal activities against Bursaphelenchus xylophilus . This is the first report of secondary metabolites in a genus Paraniesslia aquatic fungus.