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Make It Green: Copper‐Catalyzed Olefin Aziridination in Water with an Iminoiodonane
Author(s) -
Borrego Elena,
Pérez Pedro J.,
Caballero Ana
Publication year - 2021
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.202100825
Subject(s) - chemistry , nitrene , catalysis , dichloromethane , olefin fiber , copper , solvent , organic chemistry , medicinal chemistry , combinatorial chemistry
The copper complex Tp (CF3)2,Br Cu(NCMe) efficiently catalyses the aziridination of olefins in water using PhI=NTs as the nitrene source, with identical activity than that observed when using dichloromethane as the solvent, under the same experimental conditions. No specific modification of catalyst or substrates are required, nor the presence of additional phase transfer catalyst. Competition experiments and Hammett plots show that the behaviour of the metal centre is the same in both reaction media. This is the first example of a catalytic system employing PhI=NTs for olefin aziridination in water.