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Synthesis of New Ruthenium‐CAP Complexes and Use as Catalysts for Benzonitrile Hydration to Benzamide
Author(s) -
Guerriero Antonella,
Peruzzini Maurizio,
Gonsalvi Luca
Publication year - 2021
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.202100743
Subject(s) - chemistry , benzonitrile , benzamide , phosphine , catalysis , bimetallic strip , ruthenium , medicinal chemistry , nuclear magnetic resonance spectroscopy , nuclear chemistry , organic chemistry
The new bimetallic [Ru 2 (μ‐Cl) 3 (CAP) 6 ]Cl ( 1 ) and monometallic cis , cis , trans ‐[RuCl 2 (dmso‐ S ) 2 (CAP) 2 ] ( 2 ) complexes, bearing the water soluble cage‐like phosphine CAP (1,4,7‐triaza‐9‐phosphatricyclo[5.3.2.1]tridecane), were synthesized and characterized in solution by NMR spectroscopy and ESI‐MS spectrometry. The complexes, endowed with high solubility and stability in water, were applied as catalysts for the proof‐of‐concept hydration of benzonitrile to benzamide in neat water at 100 °C, achieving high conversions with only 1 mol % of catalyst, both in single runs and in catalyst recycling experiments.