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Cobaltoceniumselenolate Gold(I) Complexes: Synthesis, Spectroscopic, Structural and Anticancer Properties
Author(s) -
Menia Daniel,
Kopacka Holger,
Wurst Klaus,
Müller Thomas,
Lippmann Petra,
Ott Ingo,
Bildstein Benno
Publication year - 2021
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.202100379
Subject(s) - chemistry , homoleptic , mesoionic , selenium , stereochemistry , crystallography , metal , coordination complex , polar , combinatorial chemistry , inorganic chemistry , medicinal chemistry , organic chemistry , physics , astronomy
Cobaltoceniumselenolate is an unusual, highly air‐sensitive, mesoionic compound containing a very soft anionic selenium donor atom. Here we explore its coordination chemistry with Au(I) metal centers and show that its hetero‐ and homoleptic gold complexes are highly colored, air‐stable compounds, which were characterized by 1 H/ 13 C/ 31 P/ 77 Se NMR, IR, UV‐Vis, HR‐MS and single crystal XRD. Cytotoxicity of these polar, water‐soluble complexes was studied against various standard cancer cell lines (A549MDA‐MB‐231, HT‐29) revealing good anticancer activity of all three complexes.