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Can Particulate Matter and Nano Metal Oxide Particles Affect the Redox Cycling of Nitrosylcobalamin in Weakly Acidic Aqueous Solution?
Author(s) -
Polaczek Justyna,
Stochel Grażyna,
Eldik Rudi
Publication year - 2021
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.202100026
Subject(s) - chemistry , ascorbic acid , particulates , redox , aqueous solution , nist , oxide , nanoparticle , environmental chemistry , metal , inorganic chemistry , nanotechnology , organic chemistry , materials science , food science , natural language processing , computer science
Since air pollution is one of the most serious environmental problems, the study of the effects of particulate matter (PM) on physiological processes remains to be an important challenge for scientific communities. The presented studies form part of the project ‘Air Pollution versus Autoimmunity: Role of multiphase aqueous Inorganic Chemistry’. In these studies we examined the effect of Standard Reference Material 1648a, supplied by the US National Institute of Standards and Technology (NIST), and its inorganic constituents on the formation of nitrosylcobalamin (CblNO) in the reaction between nitrocobalamin (CblNO 2 ) and ascorbic acid in a weakly acidic medium. We monitored the reaction in the presence of urban NIST PM (SRM 1648a), plasma treated NIST PM (LAP) and a number of metal oxide nanoparticles, including redox active metal oxides. The obtained results clearly demonstrated that the presence of these different nanoparticles affected the rate of formation of CblNO but did not affect the nature of the final product. Special attention was given to systematic studies on the role of inorganic nanoparticles as a part of the selected PM in the reaction between CblNO 2 and ascorbic acid.