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Back Cover: Photochemical Properties and Structure–Activity Relationships of Ru II Complexes with Pyridylbenzazole Ligands as Promising Anticancer Agents (Eur. J. Inorg. Chem. 12/2017)
Author(s) -
Havrylyuk Dmytro,
Heidary David K.,
Nease Leona,
Parkin Sean,
Glazer Edith C.
Publication year - 2017
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.201700259
Subject(s) - chemistry , adduct , covalent bond , cover (algebra) , ligand (biochemistry) , combinatorial chemistry , stereochemistry , organic chemistry , biochemistry , receptor , mechanical engineering , engineering
This cover feature shows a selection of inorganic elements that are used in new anticancer agents described in this cluster issue. The hourglass symbolizes the time‐sensitive nature of chemotherapy treatment as well as the spatial and temporal control achieved with light‐activated compounds. The strained complex on the left can eject a ligand to form covalent adducts with DNA, while the unstrained complex on the right generates ROS. In both cases pyridylbenzazole ligands (X = CH, NH, O, S) were explored to identify the most potent anticancer agents. Details are discussed in the article by E. C. Glazer et al. on page 1687 ff (DOI: 10.1002/ejic.201601450 ).