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Photolabile Ruthenium(II)–Purine Complexes: Phototoxicity, DNA Binding, and Light‐Triggered Drug Release
Author(s) -
Chan Hazel,
Ghrayche Joy B.,
Wei Jianhua,
Renfrew Anna K.
Publication year - 2017
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.201700257
Subject(s) - ruthenium , chemistry , phototoxicity , cover (algebra) , dna , combinatorial chemistry , purine , stereochemistry , photochemistry , organic chemistry , biochemistry , enzyme , in vitro , catalysis , mechanical engineering , engineering
Invited for the cover of this issue is the group of Anna Renfrew from The University of Sydney, Australia. The cover image shows a light beam directed at a tumor. As a result of light irradiation, a photolabile ruthenium complex releases the anticancer agent 6‐mercaptopurine.