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C(sp 3 )–H Bond Activation Induced by Monohydroborane Coordination at an Iridium(III)–Phosphoramidate Complex
Author(s) -
Drover Marcus W.,
Christopherson Cheyenne J.,
Schafer Laurel L.,
Love Jennifer A.
Publication year - 2017
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.201601518
Subject(s) - phosphoramidate , chemistry , iridium , intramolecular force , borane , ligand (biochemistry) , boron , stereochemistry , crystallography , medicinal chemistry , catalysis , organic chemistry , receptor , biochemistry
The reaction of Cp*Ir III phosphoramidate (Cp* = pentamethylcyclopentadienyl) complexes with a monohydroborane (HBR 2 ; R = cyclohexyl or mesityl) generates cyclometalated Cp*Ir III complexes following two sequential intramolecular B–H and C(sp 3 )–H bond‐activation events. Preliminary mechanistic inquiry suggests that boron stabilization provided by the hemilabile phosphoramidate ligand provides a δ ‐B–H ··· [Ir] coordinated intermediate, which succumbs to borane‐induced C(sp 3 )–H bond activation.