Premium
Bioinspired Nanoparticle‐Assembly Route to a Hybrid Scaffold: Designing a Robust Heterogeneous Catalyst for Asymmetric Dihydroxylation of Olefins
Author(s) -
Shilpa Nagaraju,
Manna Joydeb,
Rana Rohit Kumar
Publication year - 2015
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.201500711
Subject(s) - chemistry , catalysis , dihydroxylation , nanoparticle , heterogeneous catalysis , combinatorial chemistry , chelation , substrate (aquarium) , enantioselective synthesis , chemical engineering , nanotechnology , organic chemistry , materials science , oceanography , geology , engineering
A hierarchical polyamine‐silica structure is shown to encase osmate ions resulting in robust and reusable catalysts for asymmetric dihydroxylation of olefins with a high TON (>700). Whilst the polypeptide and related polyamines resembling a proteinaceous matrix in biosilica nanostructures preserve the osmate as the active centre, the surrounding assembly of silica nanoparticles imparts stability and textural properties to the catalyst. This confinement of osmate in the microsphere leads to higher catalytic activity and enantioselectivity for a variety of olefins as the substrate. The hybrid nature of the catalyst not only allows for the usage of various solvent systems, but also provides a means to be integrated with multi‐components/functions for tuning the activity, catalysis separation and reusability. Interestingly, the presence of polyamine makes the catalyst retain its activity even in the presence of chelating acids like citrate that are known to diminish enantioselectivity.