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Facile One‐Pot Route toward Water‐Soluble Lanthanide–Copper–Glycinehydroximate 15‐Metallacrown‐5 Complexes
Author(s) -
Katkova Marina A.,
Zabrodina Galina S.,
Muravyeva Maria S.,
Shavyrin Andrey S.,
Baranov Evgeny V.,
Khrapichev Alexandr A.,
Ketkov Sergey Yu.
Publication year - 2015
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.201500695
Subject(s) - chemistry , denticity , lanthanide , nuclear magnetic resonance spectroscopy , copper , aqueous solution , crystallography , inorganic chemistry , stereochemistry , medicinal chemistry , ion , crystal structure , organic chemistry
Among the Ln[15MC CuRha ‐5] metallacrowns (MC; Rha = R‐substituted hydroximate ligands), the simple glycinehydroximate (Glyha) complex is presented as the primary model for studying various aspects of the guest interaction with the Ln III ion. We report a one‐pot synthesis of several glycinehydroximate LnL[15MC CuGlyha ‐5] derivatives in the presence of calcium compounds. The complexes with bidentate nitrate ion Nd(NO 3 )[15MC Cu II Glyha ‐5](NO 3 ) 2 ( 1 ), bidentate acetate Y(CH 3 COO)[15MC Cu II Glyha ‐5](NO 3 ) 2 ( 2 ), bridging nitrate La(NO 3 )[15MC Cu II Glyha ‐5](NO 3 ) 2 ( 3 ), and bidentate lactate Gd(CH 3 CHOCOO)[15MC Cu II Glyha ‐5]Cl 2 [ 4 (Gd)] have been prepared and characterized by X‐ray analysis. The lactate was chosen as an example of the essential oxy‐anions that exist as metabolites in all living organisms. We examined the lanthanide‐induced NMR spectroscopy shifting ability of a series of lactate 4 (Ln) metallacrown complexes (Ln = La, Y, Ce, Pr, Nd, Sm, Eu, Gd, Tb, or Dy). The corresponding Gd III complex was characterized by 1 H NMR spectroscopy relaxometric techniques in aqueous media.