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Carrageenan–Silica Hybrid Nanoparticles Prepared by a Non‐Emulsion Method
Author(s) -
Soares Sofia F.,
Trindade Tito,
DanieldaSilva Ana L.
Publication year - 2015
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.201500450
Subject(s) - chemistry , biopolymer , emulsion , fourier transform infrared spectroscopy , chemical engineering , nanoparticle , covalent bond , zeta potential , hybrid material , sulfonate , infrared spectroscopy , polymer , drug delivery , carrageenan , spectroscopy , polymer chemistry , organic chemistry , biochemistry , sodium , engineering , physics , quantum mechanics
Abstract Spherical and monodispersed sub‐micrometer sized particles of organic–inorganic hybrids were prepared by means of a sol–gel non‐emulsion method using the biopolymer κ‐carrageenan and the alkoxysilane 3‐isocyanatopropyltriethoxysilane (ICPTES). The structural characterization of the carrageenan–silica hybrid particles was performed by using FTIR spectroscopy and solid‐state 29 Si and 13 C NMR spectroscopy and confirmed that κ‐carrageenan was covalently linked to the siliceous network via urethane bonds. Zeta‐potential measurements indicate the hybrids were functionalized on the surface with sulfonate groups from the polysaccharide. These hybrids display thermal sensitivity, which is of great relevance for biomedical applications such as drug encapsulation and thermally controlled drug‐delivery systems.