Premium
Catalytic Diamino‐Sugar‐Assisted Enantioselective Hydrogenation
Author(s) -
Böge Matthias,
Heck Jürgen
Publication year - 2015
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.201500306
Subject(s) - chemistry , enantioselective synthesis , catalysis , ruthenium , asymmetric hydrogenation , enantiomer , sugar , enantiomeric excess , transition metal , organic chemistry , carbohydrate , combinatorial chemistry
Carbohydrate ligands have been studied in transition‐metal‐catalyzed hydrogenations in recent decades. Herein, we report the diastereoselective synthesis of trans ‐dichlorido(bisphosphane)ruthenium(II) complexes with four different methyl 2,3‐diamino‐4,6‐ O ‐benzylidene‐2,3‐dideoxy‐α‐ D ‐hexopyranosides and their application as catalyst precursors in asymmetric hydrogenation reactions. Depending on the hexopyranose, an enantiomeric excess of up to 78 % was obtained.