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Halogenolysis of a Nickelalactone Complex Produces β‐Halo‐Anhydrides
Author(s) -
Zarkesh Ryan A.,
Hopkins Michael D.,
Jordan Richard F.
Publication year - 2014
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.201402952
Subject(s) - chemistry , halogen , medicinal chemistry , reductive elimination , halo , organic chemistry , catalysis , alkyl , physics , quantum mechanics , galaxy
Nickelalactone complex [(dppe)Ni{κ 2 ‐ C , O ‐CH 2 CH 2 C(=O)O}] {dppe = 1,2‐bis(diphenylphosphino)ethane} reacts with halogens to form 3‐halo‐propionic anhydrides, [(dppe)NiX 2 ], and [(dppeO 2 ) 3 Ni][NiX 4 ] (X = Cl, Br, I). Studies of model complexes [(dppe)Ni(O 2 C t Bu) 2 ] and [(dppe)NiBr(O 2 C t Bu)] suggest that oxidation to Ni III and P–O reductive elimination are key steps in this reaction.