Premium
Highly Selective Fluorescence Detection of Hydrogen Sulfide by Using an Anthracene‐Functionalized Cyclam–Cu II Complex
Author(s) -
SantosFigueroa Luis E.,
de la Torre Cristina,
El Sayed Sameh,
Sancenón Félix,
MartínezMáñez Ramón,
Costero Ana M.,
Gil Salvador,
Parra Margarita
Publication year - 2014
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.201301306
Subject(s) - chemistry , cyclam , anthracene , fluorescence , hydrogen sulfide , photochemistry , copper , quenching (fluorescence) , aqueous solution , inorganic chemistry , metal , organic chemistry , sulfur , physics , quantum mechanics
An anthracene‐functionalised cyclam–copper(II) complex for the detection of HS – in aqueous environments has been prepared. This probe displays poor fluorescence but can selectively and sensitively detect HS – anions in water over other anions, biothiols and common oxidants such as H 2 O 2 through remarkably enhanced emission. This turn‐on response in the presence of the HS – anion is ascribed to a demetallation reaction that inhibits emission quenching observed in the initial complex as a result of the presence of the paramagnetic Cu 2+ centre. Moreover, real‐time fluorescence imaging measurements confirm that probe [Cu( 1 )] 2+ can be easily used to detect intracellular HS – at micromolar concentrations with a remarkable enhancement in the FI/FI 0 ratio.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom