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Nanoparticle‐Incorporated Functional Mesoporous Silica Colloid for Diverse Applications
Author(s) -
Sinha Arjyabaran,
Jaikhil R.
Publication year - 2012
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.201200496
Subject(s) - mesoporous material , nanorod , mesoporous silica , nanoparticle , quantum dot , nanotechnology , surface modification , chemistry , drug delivery , nanomaterials , mesoporous organosilica , nanocrystal , colloidal gold , nanomedicine , self assembly , chemical engineering , materials science , organic chemistry , catalysis , engineering
A generalized in situ synthesis approach has been developed to prepare primary‐amine‐terminated mesoporous silica particles incorporated with a wide range of nanoparticles in the size range 2–50 nm, such as quantum dots, iron oxide nanoparticles, doped semiconductor nanocrystals, and gold nanorods. The resultant mesoporous particles are 50–800 nm in size and have a primary‐amine‐terminated surface and different morphology such as isolated spheres, rods, wires, or covalently connected aggregates. These mesoporous particles can be transformed into different functional nanoparticles for diverse applications such as drug delivery, bioimaging, and water purification. Quantum dot incorporated mesoporous particles have been demonstrated as multifunctional drug delivery carriers with simultaneous use as imaging probes. Similarly, quantum dot/gold nanorod incorporated mesoporous particles have been used as cellular imaging probes and their cellular interaction/uptake have been enhanced after functionalization with oleyl or TAT peptide.