Premium
Cyanide and Carbon Monoxide Ligand Formation in Hydrogenase Biosynthesis
Author(s) -
Swanson Kevin D.,
Duffus Benjamin R.,
Beard Trevor E.,
Peters John W.,
Broderick Joan B.
Publication year - 2011
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.201190020
Subject(s) - chemistry , hydrogenase , carbon monoxide , carbon monoxide dehydrogenase , cyanide , stereochemistry , catalysis , photochemistry , crystallography , inorganic chemistry , organic chemistry
The inside cover picture shows a schematic representation of [FeFe]‐hydrogenase maturation in a microbial community in a geothermal hot spring of Yellowstone National Park, USA. In the stepwise formation of the active site H‐cluster (lower right) of the [FeFe]‐hydrogenase, carbon monoxide and cyanide ligands are synthesized from tyrosine through a radical SAM reaction catalyzed by HydG (lower left, shown here as a ribbon diagram based on a homology model). The synthesis and transfer of these diatomic ligands to the H‐cluster during hydrogenase maturation is discussed in detail in the Microrevierw by John W. Peters, Joan B. Broderick et al. (p. 935 ff ). Photograph and superimposed artwork by courtesy of Kevin Swanson.