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Mechanistic Studies on the Copper‐Catalyzed Hydrosilylation of Ketones (Eur. J. Inorg. Chem. 4/2010)
Author(s) -
Issenhuth JeanThomas,
Notter FrançoisPaul,
Dagorne Samuel,
Dedieu Alain,
BelleminLaponnaz Stéphane
Publication year - 2010
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.201090006
Subject(s) - chemistry , hydrosilylation , silane , copper , silyl ether , ketone , catalysis , alkoxy group , silylation , medicinal chemistry , polymer chemistry , computational chemistry , organic chemistry , alkyl
The cover picture shows the Aiguille du Midi, Mont Blanc massif, France. The mechanism of the copper‐catalyzed hydrosilylation of ketones has been determined by experimental mechanistic investigations and computational studies. The insertion of the ketone into the Cu–H bond was found to have a lower activation barrier than the reaction of the copper alkoxy intermediate with the silane that regenerates the Cu–H bond along with the silyl ether product, as shown in the picture. Details are discussed in the article by A. Dedieu, S. Bellemin‐Laponnaz et al. on p. 529 ff.