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Gold(I) Complexes of P,N Ligands and Their Catalytic Activity
Author(s) -
Khin Chosu,
Hashmi A. Stephen K.,
Rominger Frank
Publication year - 2010
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.200900964
Subject(s) - chemistry , catalysis , acetonitrile , ligand (biochemistry) , molar ratio , medicinal chemistry , chloride , crystal structure , stereochemistry , crystallography , organic chemistry , receptor , biochemistry
Abstract Gold(I) complexes were readily prepared by reaction of the respective ligands with (Me 2 S)AuCl in CH 2 Cl 2 . Complexes of formula LAuCl {L = diphenyl(2‐pyridyl)phosphane (PPh 2 Py), ( R )‐(+)‐4‐[(2)‐(diphenylphosphanyl)‐1‐naphthyl]‐ N ‐[( R )‐1‐phenylethyl]‐1‐phthalazinamine (PINAP)} were obtained when a 1:1 molar ratio of ligand to starting gold precursor was used. When a 2:1 ratio of ligand to gold precursor was used with PPh 2 Py or MandyPhos as ligands, complexes of the type L 2 AuCl were obtained. All complexes were fully characterized, and single‐crystal X‐ray structures could be determined for four complexes. Chloride ions were removed by reaction with silver salts, such as AgNTf 2 , AgOTf and AgBF 4 , for the use of these complexes as catalysts. After the catalytic reaction with alkynes and alcohols in acetonitrile, a unique trinuclear gold(I) complex derived from [(PPh 2 Py)Au]BF 4 could be characterized by X‐ray structural analysis, showing a mode of catalyst deactivation.