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Polyhedral Boranes for Medical Applications: Current Status and Perspectives
Author(s) -
Sivaev Igor B.,
Bregadze Vladimir V.
Publication year - 2009
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.200900003
Subject(s) - chemistry , boranes , boron , carborane , neutron capture , current (fluid) , combinatorial chemistry , nanotechnology , radiochemistry , organic chemistry , materials science , electrical engineering , engineering
This review focuses on the current status and perspectives of the application of polyhedral boron hydrides in medicine. The main topics discussed are boron neutron capture therapy for cancer and radionuclide diagnostics and therapy. X‐ray contrast diagnostics, antitumor activity of some metal derivatives of carboranes, and drug design including carborane fragments are discussed as well.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)