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Syntheses, Structures and Reactivities of [CpTc(CO) 3 X] + and [CpRe(CO) 3 X] + (Eur. J. Inorg. Chem. 27/2008)
Author(s) -
Zobi Fabio,
Spingler Bernhard,
Alberto Roger
Publication year - 2008
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.200890074
Subject(s) - chemistry , reactivity (psychology) , formate , nucleophile , yield (engineering) , lewis acids and bases , medicinal chemistry , stereochemistry , organic chemistry , catalysis , medicine , materials science , alternative medicine , pathology , metallurgy
The cover picture shows new aspects of [Cp*Re(CO) 3 Br] + and [Cp*Tc(CO) 3 Br] + chemistry. High‐yield preparation of these basic complexes (especially for 9 99 Tc) enabled a comparative exploration of the respective chemistries in water and organic solvents. The Lewis acidic Re III and Tc III centres activate the CO ligands for directed substitutions and nucleophilic attack. The reaction with CH 3 OH gave a methyl formate complex which reduced to [Cp*M(CO) 3 ] under acidic conditions. IR spectroscopy and kinetic studies with 13 C‐labelled formate revealed the source for CO in [Cp*Re(CO) 3 ]. Shown are the different colours of homologous Re and Tc complexes against a background of the Zurich lake area. The reactivity of the title compounds with alcohols implies potential for targeted inorganic medicinal chemistry if the OH group is pendent to a (radio)pharmaceutical. Details are discussed in the article by R. Alberto et al. on p. 4205 ff. We thank Dr. F. Wild for designing this picture.