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A Simple Building‐Block Route to (Phosphanyl‐carbene)palladium Complexes via Intermolecular Addition of Functionalised Phosphanes to Isocyanides
Author(s) -
Eberhard Michael R.,
van Vliet Bart,
Durán Páchon Laura,
Rothenberg Gadi,
Eastham Graham,
Kooijman Huub,
Spek Anthony L.,
Elsevier Cornelis J.
Publication year - 2009
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.200801067
Subject(s) - chemistry , carbene , sonogashira coupling , denticity , palladium , intermolecular force , combinatorial chemistry , desymmetrization , catalysis , organic chemistry , enantioselective synthesis , polymer chemistry , molecule , crystal structure
We present a straightforward protocol for making (phosphanyl‐carbene)Pd II complexes. These complexes have bidentate ligands containing an acyclic diamino‐ or aminooxy‐carbene and a phosphane. The synthesis gives good yields (typically 70–90 %) for a variety of complexes (22 compounds). Moreover, it does not require the synthesis of imidazolium salts nor the a priori generation of free carbenes. Three of the new complexes were tested as catalysts for Sonogashira and Hay coupling reactions, with good yields and selectivities. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)