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Low‐Coordinate Iron Complexes Based on Bis(pyrazolyl)borate and Their Reactivity
Author(s) -
Wagner Marit,
Limberg Christian,
Ziemer Burkhard
Publication year - 2008
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.200800314
Subject(s) - chemistry , reactivity (psychology) , boron , nucleophile , medicinal chemistry , sodium , stereochemistry , combinatorial chemistry , organic chemistry , catalysis , medicine , alternative medicine , pathology
Preparation routes for several sodium salts of diphenylbis(pyrazolyl)borates with bulky substituents are described. For a potential modelling of α‐keto‐acid‐dependent nonheme iron enzymes, mononuclear iron compounds containing those bis(pyrazolyl)borates as ligands were synthesised and structurally characterised. The iron centres are four‐coordinate (in one case only three‐coordinate) thus offering room for the binding of exogenous ligands. However, reactivity studies with carboxylates and O 2 have revealed nonuniform behaviour, and the identification of a side product in one case, combined with subsequent ESI‐MS studies, demonstrated that a pronounced sensitivity of the B–N bonds towards oxo nucleophiles could be a possible reason.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)