Palladium‐Catalysed Direct C‐H Activation/Arylation of Heteroaromatics: An Environmentally Attractive Access to Bi‐ or Polydentate Ligands | Zendy

Derridj Fazia | Zendy; Gottumukkala Aditya L. | Zendy; Djebbar Safia | Zendy; Doucet Henri | Zendy

Premium

Palladium‐Catalysed Direct C‐H Activation/Arylation of Heteroaromatics: An Environmentally Attractive Access to Bi‐ or Polydentate Ligands

Author(s) -

Derridj Fazia,

Gottumukkala Aditya L.,

Djebbar Safia,

Doucet Henri

Publication year - 2008

Publication title -

european journal of inorganic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.667

H-Index - 136

eISSN - 1099-0682

pISSN - 1434-1948

DOI - 10.1002/ejic.200800143

Subject(s) - chemistry , denticity , oxazole , palladium , nitrile , catalysis , combinatorial chemistry , medicinal chemistry , organic chemistry , crystal structure

Bi‐ or polydentate ligands based on heterocycles can be easily prepared by palladium‐catalysed C–H bond activation of heteroaromatics followed by heteroarylation with heteroaryl bromides. A variety of heteroaromatics such as furans, thiophenes, pyridines, thiazoles or oxazole derivatives have been employed and moderate to good yields were generally obtained using the air‐stable complex [PdCl(dppb)(C 3 H 5 )] as catalyst. A range of functions such as acetyl, formyl, ester or nitrile on the heteroaromatics is tolerated.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research