Premium
Transfer Hydrogenation of Ketones Catalysed by New Half‐Sandwich Ruthenium(II) Complexes Bearing the Sulfonated Phosphane ( meta ‐Sulfonatophenyl)diphenylphosphane Potassium Salt (TPPMS)
Author(s) -
Díez Josefina,
Gamasa M. Pilar,
Lastra Elena,
GarcíaFernández Almudena,
Tarazona M. Pilar
Publication year - 2006
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.200600115
Subject(s) - chemistry , catalysis , ruthenium , hydride , transfer hydrogenation , benzene , potassium , ligand (biochemistry) , solvent , salt (chemistry) , medicinal chemistry , inorganic chemistry , organic chemistry , metal , biochemistry , receptor
New half‐sandwich ruthenium(II) complexes [RuCl 2 (η 6 ‐arene)(TPPMS)] [η 6 ‐arene = p ‐cymene ( 1a ), benzene ( 1b )] and [RuCl(η 6 ‐arene)(TPPMS) 2 ][Cl] [η 6 ‐arene = p ‐cymene ( 2a ), benzene ( 2b )] containing the water‐soluble ( meta ‐sulfonatophenyl)diphenylphosphane potassium salt (TPPMS) have been synthesised. The X‐ray analysis for complex 1a revealed that, in the solid state, complex anions are held together in the crystal lattice by weak electrostatic interactions with potassium cations leading to a linear chain structure. The extent of the association in solution depends on the solvent and the determination of the size of the particles in THF can be accomplished using Multiangle Light Scattering (MALS). The new complexes proved to be excellent catalysts for transfer hydrogenation of ketones and the hydrophilic properties of the TPPMS ligand allow the catalyst recovery. The hydride derivative [RuClH(η 6 ‐ p ‐cymene)(TPPMS)] ( 4 ) has also been shown to be an efficient catalyst for these processes. Moreover, when 1a was used as catalyst, complex 4 was observed as the main product after the catalysis, supporting the implication of hydride species in transfer hydrogenation catalysis. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)