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A Pulse Radiolysis Study of Catalytic Superoxide Radical Dismutation by a Manganese( II ) Complex with an N‐Tripodal Ligand
Author(s) -
Durot Stéphanie,
Lambert François,
Renault JeanPhilippe,
Policar Clotilde
Publication year - 2005
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.200400834
Subject(s) - chemistry , radiolysis , superoxide , adduct , catalysis , manganese , ligand (biochemistry) , photochemistry , reactivity (psychology) , radical , superoxide radical , enzyme , organic chemistry , biochemistry , receptor , alternative medicine , pathology , medicine
This article presents a pulse radiolysis study of the reactivity of a SOD‐mimic Mn II complex [Mn II (IPG)] + 1 with superoxide. It uses an improved set‐up with a circulating cell. It provides convergent pieces of evidence that 1 catalyses efficiently the dismutation of superoxide. Three sets of experiments are described: (1) Transient formation and decay of an adduct labeled {MnOO} 6 were studied. (2) A multi‐pulse experiment showed a reproducible behaviour upon successive superoxide pulses. (3) Superoxide decay was monitored at 270 nm to provide an overall kinetic constant. A mechanism is proposed. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)