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Direct Synthesis of Enantiopure Tripod Ligands from C 2 ‐Symmetric Precursors
Author(s) -
Hegelmann Ina,
Burzlaff Nicolai
Publication year - 2003
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.200390056
Subject(s) - tripod (photography) , enantiopure drug , chemistry , carboxylate , ligand (biochemistry) , stereochemistry , carbon atom , methane , combinatorial chemistry , organic chemistry , enantioselective synthesis , receptor , catalysis , alkyl , physics , optics , biochemistry
A new enantiopure chiral tripod ligand is obtained from C 2 ‐symmetric bis(camphorpyrazol‐1‐yl)methane by introducing a carboxylate group at the bridging carbon atom. A prochiral centre is formed rather than an additional stereocentre. Therefore, a homochiral tripod ligand is achieved without separation of the stereoisomers. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)