Syntheses and Coordination Chemistry of Aminomethylphosphine Derivatives of Adenine

Two aminomethylphosphane derivatives of adenine 9‐(2‐{bis[(diphenylphosphanyl)methyl]amino}ethyl)adenine ( La ) and 9‐(3‐{bis[(diphenylphosphanyl)methyl]amino}propyl)adenine ( Lb ) were synthesised. Oxidation of La and Lb with H 2 O 2 , elemental sulfur or elemental selenium led to the corresponding oxidized products 4a / b − 6a / b . Both La and Lb behave as didentate ligands towards late transition metals. Reaction of La or Lb with [MX 2 (cod)] (M = Pd, Pt; X = Cl, Me) gave chelate complexes 7a / b − 10a / b . Reaction of La or Lb with [AuCl(tht)] or [{RuCl(μ‐Cl)( p ‐MeC 6 H 4 i Pr)} 2 ] gave the didentate bridging complexes 11a / b and 12a . All compounds have been fully characterised by microanalysis, IR, 1 H and 31 P{ 1 H} NMR spectroscopy, and EI/CI/FAB mass spectrometry. 1 H{ 31 P} NMR and 1 H‐ 13 C correlation experiments were used to confirm the spectral assignments where necessary. Two compounds were structurally characterised by X‐ray crystallographic analysis. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)