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Collagen type VI is the antigen recognized by the ER‐TR7 antibody
Author(s) -
Schiavinato Alvise,
Przyklenk Matthias,
Kobbe Birgit,
Paulsson Mats,
Wagener Raimund
Publication year - 2021
Publication title -
european journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.272
H-Index - 201
eISSN - 1521-4141
pISSN - 0014-2980
DOI - 10.1002/eji.202149263
Subject(s) - biology , antigen , antibody , reticular connective tissue , monoclonal antibody , lymphatic system , immunology , microbiology and biotechnology , anatomy
The monoclonal antibody ER‐TR7 was used in a great number of studies for detecting reticular fibroblasts and the ECM of lymphoid and non‐lymphoid organs even if the protein recognized by the ER‐TR7 antibody was not known. We have now identified native collagen VI microfibrils as its tissue antigen.